L489-2305 Screening compound: 2-{7-chloro-6-fluoro-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(3,5-dimethoxyphenyl)acetamide

L489-2305 Screening compound: 2-{7-chloro-6-fluoro-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(3,5-dimethoxyphenyl)acetamide
L489-2305 Screening compound: 2-{7-chloro-6-fluoro-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(3,5-dimethoxyphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L489-2305
2-{7-chloro-6-fluoro-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(3,5-dimethoxyphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L489-2305

Molecular Formula

C22H21ClFN3O4 (C22 H21 ClFN3 O4)

Compound Name

2-{7-chloro-6-fluoro-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(3,5-dimethoxyphenyl)acetamide

IUPAC name

2-{7-chloro-6-fluoro-10-oxo-1H2H3H4H5H10H-benzo[b]16-naphthyridin-2-yl}-N-(35-dimethoxyphenyl)acetamide

SMILES

COc1cc(NC(CN(CC2)CC3=C2Nc(c(F)c(cc2)Cl)c2C3=O)=O)cc(OC)c1

InChI

InChI=1S/C22H21ClFN3O4/c1-30-13-7-12(8-14(9-13)31-2)25-19(28)11-27-6-5-18-16(10-27)22(29)15-3-4-17(23)20(24)21(15)26-18/h3-4,7-9H,5-6,10-11H2,1-2H3,(H,25,28)(H,26,29)

InChI Key

VUIGFUVDOVGBDV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27457776

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.88

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.037

Distribution Coefficient, logD

1.551

Water Solubility, LogSw

-4.49

Polar Surface Area

63.899

Acid Dissociation Constant (pKa)

4.92

Base Dissociation Constant (pKb)

1.69

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

L489-2305 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L489-2305 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L489-2305?
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What is the minimum amount of L489-2305 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L489-2305
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L489-2305
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L489-2305 available by request