L489-2316 Screening compound: 2-{7-chloro-6-fluoro-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide

L489-2316 Screening compound: 2-{7-chloro-6-fluoro-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
L489-2316 Screening compound: 2-{7-chloro-6-fluoro-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L489-2316
2-{7-chloro-6-fluoro-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L489-2316

Molecular Formula

C22H19ClFN3O4 (C22 H19 ClFN3 O4)

Compound Name

2-{7-chloro-6-fluoro-10-oxo-1H,2H,3H,4H,5H,10H-benzo[b]1,6-naphthyridin-2-yl}-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide

IUPAC name

2-{7-chloro-6-fluoro-10-oxo-1H2H3H4H5H10H-benzo[b]16-naphthyridin-2-yl}-N-(23-dihydro-14-benzodioxin-6-yl)acetamide

SMILES

O=C(CN(CC1)CC2=C1Nc(c(F)c(cc1)Cl)c1C2=O)Nc(cc1)cc2c1OCCO2

InChI

InChI=1S/C22H19ClFN3O4/c23-15-3-2-13-21(20(15)24)26-16-5-6-27(10-14(16)22(13)29)11-19(28)25-12-1-4-17-18(9-12)31-8-7-30-17/h1-4,9H,5-8,10-11H2,(H,25,28)(H,26,29)

InChI Key

ZVEQGCVWFLPCIP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27457784

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.86

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.870

Distribution Coefficient, logD

0.384

Water Solubility, LogSw

-3.66

Polar Surface Area

64.634

Acid Dissociation Constant (pKa)

4.92

Base Dissociation Constant (pKb)

1.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

L489-2316 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L489-2316 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L489-2316?
Check Price and Availability of L489-2316, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L489-2316 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L489-2316
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L489-2316
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L489-2316 available by request