L491-0136 Screening compound: ethyl 2-[4-({[2-(4-fluorophenyl)-1H-indol-3-yl]carbamoyl}amino)phenyl]acetate

L491-0136 Screening compound: ethyl 2-[4-({[2-(4-fluorophenyl)-1H-indol-3-yl]carbamoyl}amino)phenyl]acetate
L491-0136 Screening compound: ethyl 2-[4-({[2-(4-fluorophenyl)-1H-indol-3-yl]carbamoyl}amino)phenyl]acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound L491-0136
ethyl 2-[4-({[2-(4-fluorophenyl)-1H-indol-3-yl]carbamoyl}amino)phenyl]acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L491-0136

Molecular Formula

C25H22FN3O3 (C25 H22 FN3 O3)

Compound Name

ethyl 2-[4-({[2-(4-fluorophenyl)-1H-indol-3-yl]carbamoyl}amino)phenyl]acetate

IUPAC name

ethyl 2-[4-({[2-(4-fluorophenyl)-1H-indol-3-yl]carbamoyl}amino)phenyl]acetate

SMILES

CCOC(Cc(cc1)ccc1NC(Nc1c(-c(cc2)ccc2F)[nH]c2c1cccc2)=O)=O

InChI

InChI=1S/C25H22FN3O3/c1-2-32-22(30)15-16-7-13-19(14-8-16)27-25(31)29-24-20-5-3-4-6-21(20)28-23(24)17-9-11-18(26)12-10-17/h3-14,28H,2,15H2,1H3,(H2,27,29,31)

InChI Key

TZIKOVYIHTZULX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27457871

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

431.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.931

Distribution Coefficient, logD

4.931

Water Solubility, LogSw

-4.78

Polar Surface Area

61.152

Acid Dissociation Constant (pKa)

13.85

Base Dissociation Constant (pKb)

-0.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.00

L491-0136 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

Indole Derivatives (10091 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Antiviral
  • Infections
  • Immune system
Structure:
  • Cyclic compounds
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L491-0136 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L491-0136?
Check Price and Availability of L491-0136, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L491-0136 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L491-0136
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L491-0136
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L491-0136 available by request