L494-0167 Screening compound: N-(2-chlorobenzyl)-2-{3-[5-(piperidinomethyl)-1,3,4-oxadiazol-2-yl]-1H-indol-1-yl}acetamide

L494-0167 Screening compound: N-(2-chlorobenzyl)-2-{3-[5-(piperidinomethyl)-1,3,4-oxadiazol-2-yl]-1H-indol-1-yl}acetamide
L494-0167 Screening compound: N-(2-chlorobenzyl)-2-{3-[5-(piperidinomethyl)-1,3,4-oxadiazol-2-yl]-1H-indol-1-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L494-0167
N-(2-chlorobenzyl)-2-{3-[5-(piperidinomethyl)-1,3,4-oxadiazol-2-yl]-1H-indol-1-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L494-0167

Molecular Formula

C25H26ClN5O2 (C25 H26 ClN5 O2)

Compound Name

N-(2-chlorobenzyl)-2-{3-[5-(piperidinomethyl)-1,3,4-oxadiazol-2-yl]-1H-indol-1-yl}acetamide

IUPAC name

N-[(2-chlorophenyl)methyl]-2-(3-{5-[(piperidin-1-yl)methyl]-134-oxadiazol-2-yl}-1H-indol-1-yl)acetamide

SMILES

O=C(Cn1c(cccc2)c2c(-c2nnc(CN3CCCCC3)o2)c1)NCc(cccc1)c1Cl

InChI

InChI=1S/C25H26ClN5O2/c26-21-10-4-2-8-18(21)14-27-23(32)16-31-15-20(19-9-3-5-11-22(19)31)25-29-28-24(33-25)17-30-12-6-1-7-13-30/h2-5,8-11,15H,1,6-7,12-14,16-17H2,(H,27,32)

InChI Key

NTBYYHFQADBGSU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27458029

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.97

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.777

Distribution Coefficient, logD

3.765

Water Solubility, LogSw

-4.12

Polar Surface Area

60.356

Acid Dissociation Constant (pKa)

12.86

Base Dissociation Constant (pKb)

5.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

L494-0167 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Indole Derivatives (10091 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Structure:
  • Cyclic compounds
  • Mimetics
Mechanism of action:
  • PPI modulators
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L494-0167 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L494-0167?
Check Price and Availability of L494-0167, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L494-0167 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L494-0167
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L494-0167
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L494-0167 available by request