L494-0318 Screening compound: N-(4-fluorophenyl)-2-(3-{5-[(4-methylpiperidin-1-yl)methyl]-1,3,4-oxadiazol-2-yl}-1H-indol-1-yl)acetamide

L494-0318 Screening compound: N-(4-fluorophenyl)-2-(3-{5-[(4-methylpiperidin-1-yl)methyl]-1,3,4-oxadiazol-2-yl}-1H-indol-1-yl)acetamide
L494-0318 Screening compound: N-(4-fluorophenyl)-2-(3-{5-[(4-methylpiperidin-1-yl)methyl]-1,3,4-oxadiazol-2-yl}-1H-indol-1-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L494-0318
N-(4-fluorophenyl)-2-(3-{5-[(4-methylpiperidin-1-yl)methyl]-1,3,4-oxadiazol-2-yl}-1H-indol-1-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L494-0318

Molecular Formula

C25H26FN5O2 (C25 H26 FN5 O2)

Compound Name

N-(4-fluorophenyl)-2-(3-{5-[(4-methylpiperidin-1-yl)methyl]-1,3,4-oxadiazol-2-yl}-1H-indol-1-yl)acetamide

IUPAC name

N-(4-fluorophenyl)-2-(3-{5-[(4-methylpiperidin-1-yl)methyl]-134-oxadiazol-2-yl}-1H-indol-1-yl)acetamide

SMILES

CC1CCN(Cc2nnc(-c3cn(CC(Nc(cc4)ccc4F)=O)c4c3cccc4)o2)CC1

InChI

InChI=1S/C25H26FN5O2/c1-17-10-12-30(13-11-17)16-24-28-29-25(33-24)21-14-31(22-5-3-2-4-20(21)22)15-23(32)27-19-8-6-18(26)7-9-19/h2-9,14,17H,10-13,15-16H2,1H3,(H,27,32)

InChI Key

UJBHLFKLKYZKJL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15128533

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.837

Distribution Coefficient, logD

3.828

Water Solubility, LogSw

-3.78

Polar Surface Area

59.034

Acid Dissociation Constant (pKa)

10.58

Base Dissociation Constant (pKb)

5.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

L494-0318 in Drug Discovery

Included in Screening Libraries

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L494-0318 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L494-0318?
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What is the minimum amount of L494-0318 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L494-0318
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L494-0318
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L494-0318 available by request