L498-0399 Screening compound: N-(3,4-dimethoxyphenyl)-4-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzamide

L498-0399 Screening compound: N-(3,4-dimethoxyphenyl)-4-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzamide
L498-0399 Screening compound: N-(3,4-dimethoxyphenyl)-4-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L498-0399
N-(3,4-dimethoxyphenyl)-4-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L498-0399

Molecular Formula

C23H18FN3O4 (C23 H18 FN3 O4)

Compound Name

N-(3,4-dimethoxyphenyl)-4-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzamide

IUPAC name

N-(34-dimethoxyphenyl)-4-[3-(4-fluorophenyl)-124-oxadiazol-5-yl]benzamide

SMILES

COc(ccc(NC(c(cc1)ccc1-c1nc(-c(cc2)ccc2F)no1)=O)c1)c1OC

InChI

InChI=1S/C23H18FN3O4/c1-29-19-12-11-18(13-20(19)30-2)25-22(28)15-3-5-16(6-4-15)23-26-21(27-31-23)14-7-9-17(24)10-8-14/h3-13H,1-2H3,(H,25,28)

InChI Key

RFTKNVRRJAFHGS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27458167

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.41

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.607

Distribution Coefficient, logD

4.606

Water Solubility, LogSw

-4.49

Polar Surface Area

69.996

Acid Dissociation Constant (pKa)

9.99

Base Dissociation Constant (pKb)

-1.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.70

L498-0399 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Cardiovascular Library (22201 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cardiovascular

References: we are preparing a list of scientific research reports with L498-0399 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L498-0399?
Check Price and Availability of L498-0399, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L498-0399 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L498-0399
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L498-0399
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L498-0399 available by request