L498-1186 Screening compound: N-(2,4-dimethoxyphenyl)-4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzamide

L498-1186 Screening compound: N-(2,4-dimethoxyphenyl)-4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzamide
L498-1186 Screening compound: N-(2,4-dimethoxyphenyl)-4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L498-1186
N-(2,4-dimethoxyphenyl)-4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L498-1186

Molecular Formula

C23H18FN3O4 (C23 H18 FN3 O4)

Compound Name

N-(2,4-dimethoxyphenyl)-4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzamide

IUPAC name

N-(24-dimethoxyphenyl)-4-[3-(3-fluorophenyl)-124-oxadiazol-5-yl]benzamide

SMILES

COc(cc1)cc(OC)c1NC(c(cc1)ccc1-c1nc(-c2cccc(F)c2)no1)=O

InChI

InChI=1S/C23H18FN3O4/c1-29-18-10-11-19(20(13-18)30-2)25-22(28)14-6-8-15(9-7-14)23-26-21(27-31-23)16-4-3-5-17(24)12-16/h3-13H,1-2H3,(H,25,28)

InChI Key

WMDFMASXFHBLOW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27458215

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.41

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.107

Distribution Coefficient, logD

5.104

Water Solubility, LogSw

-5.06

Polar Surface Area

69.212

Acid Dissociation Constant (pKa)

9.52

Base Dissociation Constant (pKb)

-1.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.70

L498-1186 in Drug Discovery

Included in Screening Libraries

Cardiovascular Library (22201 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular

References: we are preparing a list of scientific research reports with L498-1186 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L498-1186?
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What is the minimum amount of L498-1186 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L498-1186
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L498-1186
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L498-1186 available by request