L498-1459 Screening compound: 4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}benzamide

L498-1459 Screening compound: 4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}benzamide
L498-1459 Screening compound: 4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L498-1459
4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L498-1459

Molecular Formula

C27H25F2N5O2 (C27 H25 F2 N5 O2)

Compound Name

4-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}benzamide

IUPAC name

4-[3-(3-fluorophenyl)-124-oxadiazol-5-yl]-N-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}benzamide

SMILES

O=C(c(cc1)ccc1-c1nc(-c2cc(F)ccc2)no1)NCCN(CC1)CCN1c(cccc1)c1F

InChI

InChI=1S/C27H25F2N5O2/c28-22-5-3-4-21(18-22)25-31-27(36-32-25)20-10-8-19(9-11-20)26(35)30-12-13-33-14-16-34(17-15-33)24-7-2-1-6-23(24)29/h1-11,18H,12-17H2,(H,30,35)

InChI Key

CBHZOPMZBNUWCT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27458250

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

489.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.811

Distribution Coefficient, logD

4.801

Water Solubility, LogSw

-4.82

Polar Surface Area

62.841

Acid Dissociation Constant (pKa)

12.57

Base Dissociation Constant (pKb)

5.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

L498-1459 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with L498-1459 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L498-1459?
Check Price and Availability of L498-1459, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L498-1459 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L498-1459
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L498-1459
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L498-1459 available by request