L499-0524 Screening compound: 1-{3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzoyl}-4-(pyridin-2-yl)piperazine

L499-0524 Screening compound: 1-{3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzoyl}-4-(pyridin-2-yl)piperazine
L499-0524 Screening compound: 1-{3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzoyl}-4-(pyridin-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L499-0524
1-{3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzoyl}-4-(pyridin-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L499-0524

Molecular Formula

C24H20FN5O2 (C24 H20 FN5 O2)

Compound Name

1-{3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzoyl}-4-(pyridin-2-yl)piperazine

IUPAC name

1-{3-[3-(4-fluorophenyl)-124-oxadiazol-5-yl]benzoyl}-4-(pyridin-2-yl)piperazine

SMILES

O=C(c1cccc(-c2nc(-c(cc3)ccc3F)no2)c1)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C24H20FN5O2/c25-20-9-7-17(8-10-20)22-27-23(32-28-22)18-4-3-5-19(16-18)24(31)30-14-12-29(13-15-30)21-6-1-2-11-26-21/h1-11,16H,12-15H2

InChI Key

ZPNQFLMJIQMVCL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27458336

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.45

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.353

Distribution Coefficient, logD

4.344

Water Solubility, LogSw

-4.51

Polar Surface Area

60.064

Acid Dissociation Constant (pKa)

24.69

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

L499-0524 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with L499-0524 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L499-0524?
Check Price and Availability of L499-0524, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L499-0524 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L499-0524
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L499-0524
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L499-0524 available by request