L500-0177 Screening compound: 1-(2-fluorophenyl)-4-(1-{[4-(5-methyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperidine-4-carbonyl)piperazine

L500-0177 Screening compound: 1-(2-fluorophenyl)-4-(1-{[4-(5-methyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperidine-4-carbonyl)piperazine
L500-0177 Screening compound: 1-(2-fluorophenyl)-4-(1-{[4-(5-methyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperidine-4-carbonyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L500-0177
1-(2-fluorophenyl)-4-(1-{[4-(5-methyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperidine-4-carbonyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L500-0177

Molecular Formula

C23H26FN5O4S2 (C23 H26 FN5 O4 S2)

Compound Name

1-(2-fluorophenyl)-4-(1-{[4-(5-methyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperidine-4-carbonyl)piperazine

IUPAC name

1-(2-fluorophenyl)-4-(1-{[4-(5-methyl-124-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperidine-4-carbonyl)piperazine

SMILES

Cc1nc(-c2csc(S(N(CC3)CCC3C(N(CC3)CCN3c(cccc3)c3F)=O)(=O)=O)c2)no1

InChI

InChI=1S/C23H26FN5O4S2/c1-16-25-22(26-33-16)18-14-21(34-15-18)35(31,32)29-8-6-17(7-9-29)23(30)28-12-10-27(11-13-28)20-5-3-2-4-19(20)24/h2-5,14-15,17H,6-13H2,1H3

InChI Key

KNOVNWGPQSJEAI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27458449

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

519.62

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.173

Distribution Coefficient, logD

3.173

Water Solubility, LogSw

-3.55

Polar Surface Area

83.481

Acid Dissociation Constant (pKa)

23.63

Base Dissociation Constant (pKb)

4.98

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.50

L500-0177 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with L500-0177 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L500-0177?
Check Price and Availability of L500-0177, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L500-0177 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L500-0177
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L500-0177
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L500-0177 available by request