L501-1241 Screening compound: 1-(1-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperidine-3-carbonyl)-2,3-dihydro-1H-indole

Chemical Structure Depiction of ChemDiv screening compound L501-1241
1-(1-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperidine-3-carbonyl)-2,3-dihydro-1H-indole

Available from 1 mg

Formats:

Glass Vials (4ml Glass Vials VWR #97047-678)
96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Check Price and Availability

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L501-1241

Molecular Formula

C₂₄H₂₆N₄O₄S₂ (C24 H26 N4 O4 S2)

Compound Name

1-(1-{[4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperidine-3-carbonyl)-2,3-dihydro-1H-indole

IUPAC name

1-(1-{[4-(5-cyclobutyl-124-oxadiazol-3-yl)thiophen-2-yl]sulfonyl}piperidine-3-carbonyl)-23-dihydro-1H-indole

SMILES

O=C(C(CCC1)CN1S(c1cc(-c2noc(C3CCC3)n2)cs1)(=O)=O)N(CC1)c2c1cccc2

InChI

InChI=1S/C24H26N4O4S2/c29-24(28-12-10-16-5-1-2-9-20(16)28)18-8-4-11-27(14-18)34(30,31)21-13-19(15-33-21)22-25-23(32-26-22)17-6-3-7-17/h1-2,5,9,13,15,17-18H,3-4,6-8,10-12,14H2/t18-/m0/s1

InChI Key

VFYSQUMPLBWFNR-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27458812

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.63

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

Partition Coefficient, logP

4.006

Distribution Coefficient, logD

4.006

Water Solubility, LogSw

-4.22

Polar Surface Area

80.509

Acid Dissociation Constant (pK_a)

21.14

Base Dissociation Constant (pK_b)

-0.78

Number of Chiral Centers

1.00

Percent sp³ carbon bonding

45.80

L501-1241 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Peptidomimetic Library (37031 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Mechanism of action:

PPI modulators
Epigenetic
PPI modulators

Structure:

Mimetics
Mimetics

Therapeutical areas:

Cancer
Musculoskeletal
Digestive system
Respiratory tract
Male
Female
Hemic and lymphatic
Metabolic
Cancer
Digestive system
Respiratory tract
Otorhinolaryngologic
Nervous system
Hemic and lymphatic
Cardiovascular
Cancer
Nervous system
Male
Female
Hemic and lymphatic
Skin
Endocrine

Targets:

Others
Kinases
Phosphatases

References: we are preparing a list of scientific research reports with L501-1241 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L501-1241?
Check Price and Availability of L501-1241, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.

What is the minimum amount of L501-1241 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.

Delivery options for L501-1241
ChemDiv sends parcels with Express services (UPS, WC).

1–2 days for small orders
2–4 weeks for large selections

Delivery formats for L501-1241

0.5–50 mg of dry powder sample in single glass vials, custom vials
DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L501-1241 available by request