L502-1391 Screening compound: 4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)-N~2~-(2-oxo-2-piperidinoethyl)-2-thiophenesulfonamide

L502-1391 Screening compound: 4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)-N~2~-(2-oxo-2-piperidinoethyl)-2-thiophenesulfonamide
L502-1391 Screening compound: 4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)-N~2~-(2-oxo-2-piperidinoethyl)-2-thiophenesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L502-1391
4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)-N~2~-(2-oxo-2-piperidinoethyl)-2-thiophenesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L502-1391

Molecular Formula

C17H22N4O4S2 (C17 H22 N4 O4 S2)

Compound Name

4-(5-cyclobutyl-1,2,4-oxadiazol-3-yl)-N~2~-(2-oxo-2-piperidinoethyl)-2-thiophenesulfonamide

IUPAC name

4-(5-cyclobutyl-124-oxadiazol-3-yl)-N-[2-oxo-2-(piperidin-1-yl)ethyl]thiophene-2-sulfonamide

SMILES

O=C(CNS(c1cc(-c2noc(C3CCC3)n2)cs1)(=O)=O)N1CCCCC1

InChI

InChI=1S/C17H22N4O4S2/c22-14(21-7-2-1-3-8-21)10-18-27(23,24)15-9-13(11-26-15)16-19-17(25-20-16)12-5-4-6-12/h9,11-12,18H,1-8,10H2

InChI Key

DPEFGTYLTLBWMP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27458863

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.52

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.555

Distribution Coefficient, logD

2.543

Water Solubility, LogSw

-2.82

Polar Surface Area

91.336

Acid Dissociation Constant (pKa)

8.97

Base Dissociation Constant (pKb)

-0.67

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

58.82

L502-1391 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L502-1391 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L502-1391?
Check Price and Availability of L502-1391, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L502-1391 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L502-1391
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L502-1391
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L502-1391 available by request