L503-0524 Screening compound: 2-(3,3-dimethyl-5-{[4-(pyridin-2-yl)piperazin-1-yl]sulfonyl}-2,3-dihydro-1H-indol-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one

L503-0524 Screening compound: 2-(3,3-dimethyl-5-{[4-(pyridin-2-yl)piperazin-1-yl]sulfonyl}-2,3-dihydro-1H-indol-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one
L503-0524 Screening compound: 2-(3,3-dimethyl-5-{[4-(pyridin-2-yl)piperazin-1-yl]sulfonyl}-2,3-dihydro-1H-indol-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L503-0524
2-(3,3-dimethyl-5-{[4-(pyridin-2-yl)piperazin-1-yl]sulfonyl}-2,3-dihydro-1H-indol-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L503-0524

Molecular Formula

C25H33N5O3S (C25 H33 N5 O3 S)

Compound Name

2-(3,3-dimethyl-5-{[4-(pyridin-2-yl)piperazin-1-yl]sulfonyl}-2,3-dihydro-1H-indol-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one

IUPAC name

2-(33-dimethyl-5-{[4-(pyridin-2-yl)piperazin-1-yl]sulfonyl}-23-dihydro-1H-indol-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one

SMILES

CC1(C)c(cc(cc2)S(N(CC3)CCN3c3ncccc3)(=O)=O)c2N(CC(N2CCCC2)=O)C1

InChI

InChI=1S/C25H33N5O3S/c1-25(2)19-29(18-24(31)28-11-5-6-12-28)22-9-8-20(17-21(22)25)34(32,33)30-15-13-27(14-16-30)23-7-3-4-10-26-23/h3-4,7-10,17H,5-6,11-16,18-19H2,1-2H3

InChI Key

LCWUUGSZHCGJBV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15128974

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

483.63

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.544

Distribution Coefficient, logD

3.520

Water Solubility, LogSw

-3.89

Polar Surface Area

63.342

Acid Dissociation Constant (pKa)

21.78

Base Dissociation Constant (pKb)

6.16

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.00

L503-0524 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L503-0524 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L503-0524?
Check Price and Availability of L503-0524, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L503-0524 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L503-0524
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L503-0524
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L503-0524 available by request