L503-0548 Screening compound: 3,3-dimethyl-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-N-[(thiophen-2-yl)methyl]-2,3-dihydro-1H-indole-5-sulfonamide

L503-0548 Screening compound: 3,3-dimethyl-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-N-[(thiophen-2-yl)methyl]-2,3-dihydro-1H-indole-5-sulfonamide
L503-0548 Screening compound: 3,3-dimethyl-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-N-[(thiophen-2-yl)methyl]-2,3-dihydro-1H-indole-5-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L503-0548
3,3-dimethyl-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-N-[(thiophen-2-yl)methyl]-2,3-dihydro-1H-indole-5-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L503-0548

Molecular Formula

C21H27N3O3S2 (C21 H27 N3 O3 S2)

Compound Name

3,3-dimethyl-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-N-[(thiophen-2-yl)methyl]-2,3-dihydro-1H-indole-5-sulfonamide

IUPAC name

33-dimethyl-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-N-[(thiophen-2-yl)methyl]-23-dihydro-1H-indole-5-sulfonamide

SMILES

CC1(C)c(cc(cc2)S(NCc3cccs3)(=O)=O)c2N(CC(N2CCCC2)=O)C1

InChI

InChI=1S/C21H27N3O3S2/c1-21(2)15-24(14-20(25)23-9-3-4-10-23)19-8-7-17(12-18(19)21)29(26,27)22-13-16-6-5-11-28-16/h5-8,11-12,22H,3-4,9-10,13-15H2,1-2H3

InChI Key

ATTHKELGWVAYSR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15128987

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

433.6

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.481

Distribution Coefficient, logD

3.481

Water Solubility, LogSw

-3.92

Polar Surface Area

62.636

Acid Dissociation Constant (pKa)

10.05

Base Dissociation Constant (pKb)

-0.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.60

L503-0548 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L503-0548 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L503-0548?
Check Price and Availability of L503-0548, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L503-0548 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L503-0548
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L503-0548
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L503-0548 available by request