L507-0948 Screening compound: 1,2-dimethyl-N-(5-methyl-1,2-oxazol-3-yl)-5-[4-methyl-5-(morpholine-4-carbonyl)-1,3-thiazol-2-yl]-1H-pyrrole-3-sulfonamide

L507-0948 Screening compound: 1,2-dimethyl-N-(5-methyl-1,2-oxazol-3-yl)-5-[4-methyl-5-(morpholine-4-carbonyl)-1,3-thiazol-2-yl]-1H-pyrrole-3-sulfonamide
L507-0948 Screening compound: 1,2-dimethyl-N-(5-methyl-1,2-oxazol-3-yl)-5-[4-methyl-5-(morpholine-4-carbonyl)-1,3-thiazol-2-yl]-1H-pyrrole-3-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L507-0948
1,2-dimethyl-N-(5-methyl-1,2-oxazol-3-yl)-5-[4-methyl-5-(morpholine-4-carbonyl)-1,3-thiazol-2-yl]-1H-pyrrole-3-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L507-0948

Molecular Formula

C19H23N5O5S2 (C19 H23 N5 O5 S2)

Compound Name

1,2-dimethyl-N-(5-methyl-1,2-oxazol-3-yl)-5-[4-methyl-5-(morpholine-4-carbonyl)-1,3-thiazol-2-yl]-1H-pyrrole-3-sulfonamide

IUPAC name

12-dimethyl-N-(5-methyl-12-oxazol-3-yl)-5-[4-methyl-5-(morpholine-4-carbonyl)-13-thiazol-2-yl]-1H-pyrrole-3-sulfonamide

SMILES

Cc1cc(NS(c2c(C)n(C)c(-c3nc(C)c(C(N4CCOCC4)=O)s3)c2)(=O)=O)no1

InChI

InChI=1S/C19H23N5O5S2/c1-11-9-16(21-29-11)22-31(26,27)15-10-14(23(4)13(15)3)18-20-12(2)17(30-18)19(25)24-5-7-28-8-6-24/h9-10H,5-8H2,1-4H3,(H,21,22)

InChI Key

REZIKWZGCHRTIE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27459356

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.55

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.696

Distribution Coefficient, logD

-0.374

Water Solubility, LogSw

-2.55

Polar Surface Area

99.584

Acid Dissociation Constant (pKa)

5.33

Base Dissociation Constant (pKb)

2.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.10

L507-0948 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Kinases
  • Others
  • Kinases
  • GPCR
Mechanism of action:
  • Epigenetic
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L507-0948 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L507-0948?
Check Price and Availability of L507-0948, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L507-0948 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L507-0948
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L507-0948
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L507-0948 available by request