L507-1985 Screening compound: 1,2-dimethyl-5-[4-methyl-5-(pyrrolidine-1-carbonyl)-1,3-thiazol-2-yl]-N-(3-methylpyridin-2-yl)-1H-pyrrole-3-sulfonamide

L507-1985 Screening compound: 1,2-dimethyl-5-[4-methyl-5-(pyrrolidine-1-carbonyl)-1,3-thiazol-2-yl]-N-(3-methylpyridin-2-yl)-1H-pyrrole-3-sulfonamide
L507-1985 Screening compound: 1,2-dimethyl-5-[4-methyl-5-(pyrrolidine-1-carbonyl)-1,3-thiazol-2-yl]-N-(3-methylpyridin-2-yl)-1H-pyrrole-3-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L507-1985
1,2-dimethyl-5-[4-methyl-5-(pyrrolidine-1-carbonyl)-1,3-thiazol-2-yl]-N-(3-methylpyridin-2-yl)-1H-pyrrole-3-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L507-1985

Molecular Formula

C21H25N5O3S2 (C21 H25 N5 O3 S2)

Compound Name

1,2-dimethyl-5-[4-methyl-5-(pyrrolidine-1-carbonyl)-1,3-thiazol-2-yl]-N-(3-methylpyridin-2-yl)-1H-pyrrole-3-sulfonamide

IUPAC name

12-dimethyl-5-[4-methyl-5-(pyrrolidine-1-carbonyl)-13-thiazol-2-yl]-N-(3-methylpyridin-2-yl)-1H-pyrrole-3-sulfonamide

SMILES

Cc(n(C)c(-c1nc(C)c(C(N2CCCC2)=O)s1)c1)c1S(Nc1ncccc1C)(=O)=O

InChI

InChI=1S/C21H25N5O3S2/c1-13-8-7-9-22-19(13)24-31(28,29)17-12-16(25(4)15(17)3)20-23-14(2)18(30-20)21(27)26-10-5-6-11-26/h7-9,12H,5-6,10-11H2,1-4H3,(H,22,24)

InChI Key

JZTAUDSSIXICEZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27459460

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

459.59

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.004

Distribution Coefficient, logD

2.611

Water Solubility, LogSw

-3.35

Polar Surface Area

79.933

Acid Dissociation Constant (pKa)

7.23

Base Dissociation Constant (pKb)

2.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

L507-1985 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L507-1985 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L507-1985?
Check Price and Availability of L507-1985, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L507-1985 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L507-1985
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L507-1985
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L507-1985 available by request