L514-0208 Screening compound: N~1~-(3,4-DIMETHYLPHENYL)-N~2~-[(2-PHENYL-1,3-THIAZOL-4-YL)METHYL]PYRROLIDINE-1,2-DICARBOXAMIDE

L514-0208 Screening compound: N~1~-(3,4-DIMETHYLPHENYL)-N~2~-[(2-PHENYL-1,3-THIAZOL-4-YL)METHYL]PYRROLIDINE-1,2-DICARBOXAMIDE
L514-0208 Screening compound: N~1~-(3,4-DIMETHYLPHENYL)-N~2~-[(2-PHENYL-1,3-THIAZOL-4-YL)METHYL]PYRROLIDINE-1,2-DICARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L514-0208
N~1~-(3,4-DIMETHYLPHENYL)-N~2~-[(2-PHENYL-1,3-THIAZOL-4-YL)METHYL]PYRROLIDINE-1,2-DICARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L514-0208

Molecular Formula

C24H26N4O2S (C24 H26 N4 O2 S)

Compound Name

N~1~-(3,4-DIMETHYLPHENYL)-N~2~-[(2-PHENYL-1,3-THIAZOL-4-YL)METHYL]PYRROLIDINE-1,2-DICARBOXAMIDE

IUPAC name

n/a

SMILES

Cc(cc1)c(C)cc1NC(N(CCC1)C1C(NCc1csc(-c2ccccc2)n1)=O)=O

InChI

InChI=1S/C24H26N4O2S/c1-16-10-11-19(13-17(16)2)27-24(30)28-12-6-9-21(28)22(29)25-14-20-15-31-23(26-20)18-7-4-3-5-8-18/h3-5,7-8,10-11,13,15,21H,6,9,12,14H2,1-2H3,(H,25,29)(H,27,30)/t21-/m0/s1

InChI Key

XORZYHXDTRUTLT-NRFANRHFSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.56

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.621

Distribution Coefficient, logD

4.621

Water Solubility, LogSw

-4.25

Polar Surface Area

60.410

Acid Dissociation Constant (pKa)

13.66

Base Dissociation Constant (pKb)

1.20

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

29.20

L514-0208 in Drug Discovery

Included in Screening Libraries

3D Mimetics PPI Library (1617 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Epigenetics Focused Set (26518 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Structure:
  • Mimetics
  • 3D
  • Cyclic compounds
  • Mimetics
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with L514-0208 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L514-0208?
Check Price and Availability of L514-0208, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L514-0208 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L514-0208
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L514-0208
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L514-0208 available by request