L514-0224 Screening compound: N~1~-(4-ETHOXYPHENYL)-N~2~-[(2-PHENYL-1,3-THIAZOL-4-YL)METHYL]PYRROLIDINE-1,2-DICARBOXAMIDE

L514-0224 Screening compound: N~1~-(4-ETHOXYPHENYL)-N~2~-[(2-PHENYL-1,3-THIAZOL-4-YL)METHYL]PYRROLIDINE-1,2-DICARBOXAMIDE
L514-0224 Screening compound: N~1~-(4-ETHOXYPHENYL)-N~2~-[(2-PHENYL-1,3-THIAZOL-4-YL)METHYL]PYRROLIDINE-1,2-DICARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L514-0224
N~1~-(4-ETHOXYPHENYL)-N~2~-[(2-PHENYL-1,3-THIAZOL-4-YL)METHYL]PYRROLIDINE-1,2-DICARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L514-0224

Molecular Formula

C24H26N4O3S (C24 H26 N4 O3 S)

Compound Name

N~1~-(4-ETHOXYPHENYL)-N~2~-[(2-PHENYL-1,3-THIAZOL-4-YL)METHYL]PYRROLIDINE-1,2-DICARBOXAMIDE

IUPAC name

n/a

SMILES

CCOc(cc1)ccc1NC(N(CCC1)C1C(NCc1csc(-c2ccccc2)n1)=O)=O

InChI

InChI=1S/C24H26N4O3S/c1-2-31-20-12-10-18(11-13-20)27-24(30)28-14-6-9-21(28)22(29)25-15-19-16-32-23(26-19)17-7-4-3-5-8-17/h3-5,7-8,10-13,16,21H,2,6,9,14-15H2,1H3,(H,25,29)(H,27,30)/t21-/m0/s1

InChI Key

KWBQRUPFYVEANS-NRFANRHFSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.56

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.003

Distribution Coefficient, logD

4.003

Water Solubility, LogSw

-3.87

Polar Surface Area

67.534

Acid Dissociation Constant (pKa)

13.66

Base Dissociation Constant (pKb)

1.84

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

29.20

L514-0224 in Drug Discovery

Included in Screening Libraries

3D Mimetics PPI Library (1617 compounds)

PI3K-Targeted Library (17255 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Structure:
  • Mimetics
  • 3D
  • Mimetics
  • Mimetics
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with L514-0224 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L514-0224?
Check Price and Availability of L514-0224, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L514-0224 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L514-0224
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L514-0224
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L514-0224 available by request