L516-0199 Screening compound: 1-[(2-OXO-2,3-DIHYDRO-1,3-BENZOXAZOL-6-YL)SULFONYL]-N-[(2-PHENYL-1,3-THIAZOL-4-YL)METHYL]PIPERIDINE-4-CARBOXAMIDE

L516-0199 Screening compound: 1-[(2-OXO-2,3-DIHYDRO-1,3-BENZOXAZOL-6-YL)SULFONYL]-N-[(2-PHENYL-1,3-THIAZOL-4-YL)METHYL]PIPERIDINE-4-CARBOXAMIDE
L516-0199 Screening compound: 1-[(2-OXO-2,3-DIHYDRO-1,3-BENZOXAZOL-6-YL)SULFONYL]-N-[(2-PHENYL-1,3-THIAZOL-4-YL)METHYL]PIPERIDINE-4-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L516-0199
1-[(2-OXO-2,3-DIHYDRO-1,3-BENZOXAZOL-6-YL)SULFONYL]-N-[(2-PHENYL-1,3-THIAZOL-4-YL)METHYL]PIPERIDINE-4-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L516-0199

Molecular Formula

C23H22N4O5S2 (C23 H22 N4 O5 S2)

Compound Name

1-[(2-OXO-2,3-DIHYDRO-1,3-BENZOXAZOL-6-YL)SULFONYL]-N-[(2-PHENYL-1,3-THIAZOL-4-YL)METHYL]PIPERIDINE-4-CARBOXAMIDE

IUPAC name

n/a

SMILES

O=C(C(CC1)CCN1S(c(cc1)cc(O2)c1NC2=O)(=O)=O)NCc1csc(-c2ccccc2)n1

InChI

InChI=1S/C23H22N4O5S2/c28-21(24-13-17-14-33-22(25-17)16-4-2-1-3-5-16)15-8-10-27(11-9-15)34(30,31)18-6-7-19-20(12-18)32-23(29)26-19/h1-7,12,14-15H,8-11,13H2,(H,24,28)(H,26,29)

InChI Key

PDELTPAWNANCCH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15129111

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.58

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.023

Distribution Coefficient, logD

2.990

Water Solubility, LogSw

-3.57

Polar Surface Area

100.010

Acid Dissociation Constant (pKa)

8.49

Base Dissociation Constant (pKb)

-0.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

L516-0199 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L516-0199 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L516-0199?
Check Price and Availability of L516-0199, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L516-0199 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L516-0199
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L516-0199
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L516-0199 available by request