L519-0144 Screening compound: N-[(2-METHYL-1,3-THIAZOL-4-YL)METHYL]-3-{[4-(PROPIONYLAMINO)PHENYL]SULFONYL}-1,3-THIAZOLIDINE-4-CARBOXAMIDE

L519-0144 Screening compound: N-[(2-METHYL-1,3-THIAZOL-4-YL)METHYL]-3-{[4-(PROPIONYLAMINO)PHENYL]SULFONYL}-1,3-THIAZOLIDINE-4-CARBOXAMIDE
L519-0144 Screening compound: N-[(2-METHYL-1,3-THIAZOL-4-YL)METHYL]-3-{[4-(PROPIONYLAMINO)PHENYL]SULFONYL}-1,3-THIAZOLIDINE-4-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L519-0144
N-[(2-METHYL-1,3-THIAZOL-4-YL)METHYL]-3-{[4-(PROPIONYLAMINO)PHENYL]SULFONYL}-1,3-THIAZOLIDINE-4-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L519-0144

Molecular Formula

C18H22N4O4S3 (C18 H22 N4 O4 S3)

Compound Name

N-[(2-METHYL-1,3-THIAZOL-4-YL)METHYL]-3-{[4-(PROPIONYLAMINO)PHENYL]SULFONYL}-1,3-THIAZOLIDINE-4-CARBOXAMIDE

IUPAC name

n/a

SMILES

CCC(Nc(cc1)ccc1S(N(CSC1)C1C(NCc1csc(C)n1)=O)(=O)=O)=O

InChI

InChI=1S/C18H22N4O4S3/c1-3-17(23)21-13-4-6-15(7-5-13)29(25,26)22-11-27-10-16(22)18(24)19-8-14-9-28-12(2)20-14/h4-7,9,16H,3,8,10-11H2,1-2H3,(H,19,24)(H,21,23)/t16-/m0/s1

InChI Key

TXZIJCARWCMRIF-INIZCTEOSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

454.6

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.940

Distribution Coefficient, logD

1.940

Water Solubility, LogSw

-2.74

Polar Surface Area

90.644

Acid Dissociation Constant (pKa)

10.28

Base Dissociation Constant (pKb)

1.99

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.90

L519-0144 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Targeted Diversity Library (40567 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with L519-0144 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L519-0144?
Check Price and Availability of L519-0144, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L519-0144 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L519-0144
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L519-0144
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L519-0144 available by request