L520-0456 Screening compound: 3-(3-CYCLOPENTYLPROPANOYL)-N-{[2-(2-THIENYL)-1,3-THIAZOL-4-YL]METHYL}-1,3-THIAZOLIDINE-4-CARBOXAMIDE

L520-0456 Screening compound: 3-(3-CYCLOPENTYLPROPANOYL)-N-{[2-(2-THIENYL)-1,3-THIAZOL-4-YL]METHYL}-1,3-THIAZOLIDINE-4-CARBOXAMIDE
L520-0456 Screening compound: 3-(3-CYCLOPENTYLPROPANOYL)-N-{[2-(2-THIENYL)-1,3-THIAZOL-4-YL]METHYL}-1,3-THIAZOLIDINE-4-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L520-0456
3-(3-CYCLOPENTYLPROPANOYL)-N-{[2-(2-THIENYL)-1,3-THIAZOL-4-YL]METHYL}-1,3-THIAZOLIDINE-4-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L520-0456

Molecular Formula

C20H25N3O2S3 (C20 H25 N3 O2 S3)

Compound Name

3-(3-CYCLOPENTYLPROPANOYL)-N-{[2-(2-THIENYL)-1,3-THIAZOL-4-YL]METHYL}-1,3-THIAZOLIDINE-4-CARBOXAMIDE

IUPAC name

n/a

SMILES

O=C(CCC1CCCC1)N(CSC1)C1C(NCc1csc(-c2cccs2)n1)=O

InChI

InChI=1S/C20H25N3O2S3/c24-18(8-7-14-4-1-2-5-14)23-13-26-12-16(23)19(25)21-10-15-11-28-20(22-15)17-6-3-9-27-17/h3,6,9,11,14,16H,1-2,4-5,7-8,10,12-13H2,(H,21,25)/t16-/m0/s1

InChI Key

ZLGKTDIGNCDQSA-INIZCTEOSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

435.64

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.283

Distribution Coefficient, logD

4.283

Water Solubility, LogSw

-4.31

Polar Surface Area

52.626

Acid Dissociation Constant (pKa)

13.83

Base Dissociation Constant (pKb)

1.04

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

55.00

L520-0456 in Drug Discovery

Included in Screening Libraries

3D Mimetics PPI Library (1617 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Anti-HIV1 Library (19540 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Structure:
  • Mimetics
  • 3D
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic
  • PPI modulators

References: we are preparing a list of scientific research reports with L520-0456 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L520-0456?
Check Price and Availability of L520-0456, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L520-0456 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L520-0456
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L520-0456
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L520-0456 available by request