L523-0171 Screening compound: N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4'-(piperidine-1-sulfonyl)-[1,1'-biphenyl]-3-carboxamide

L523-0171 Screening compound: N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4'-(piperidine-1-sulfonyl)-[1,1'-biphenyl]-3-carboxamide
L523-0171 Screening compound: N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4'-(piperidine-1-sulfonyl)-[1,1'-biphenyl]-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L523-0171
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4'-(piperidine-1-sulfonyl)-[1,1'-biphenyl]-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L523-0171

Molecular Formula

C26H26N2O5S (C26 H26 N2 O5 S)

Compound Name

N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4'-(piperidine-1-sulfonyl)-[1,1'-biphenyl]-3-carboxamide

IUPAC name

N-(23-dihydro-14-benzodioxin-6-yl)-4'-(piperidine-1-sulfonyl)-[11'-biphenyl]-3-carboxamide

SMILES

O=C(c1cccc(-c(cc2)ccc2S(N2CCCCC2)(=O)=O)c1)Nc(cc1)cc2c1OCCO2

InChI

InChI=1S/C26H26N2O5S/c29-26(27-22-9-12-24-25(18-22)33-16-15-32-24)21-6-4-5-20(17-21)19-7-10-23(11-8-19)34(30,31)28-13-2-1-3-14-28/h4-12,17-18H,1-3,13-16H2,(H,27,29)

InChI Key

KTGZJYBOHSSKOB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15129447

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.57

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.918

Distribution Coefficient, logD

3.918

Water Solubility, LogSw

-4.19

Polar Surface Area

70.592

Acid Dissociation Constant (pKa)

10.40

Base Dissociation Constant (pKb)

-2.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.90

L523-0171 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Lipid Metabolism Library (9174 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cardiovascular
  • Metabolic
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • GPCR
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L523-0171 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L523-0171?
Check Price and Availability of L523-0171, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L523-0171 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L523-0171
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L523-0171
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L523-0171 available by request