L527-0263 Screening compound: N-({3-cyclopropyl-3H-imidazo[4,5-b]pyridin-2-yl}methyl)-4-fluorobenzene-1-sulfonamide

L527-0263 Screening compound: N-({3-cyclopropyl-3H-imidazo[4,5-b]pyridin-2-yl}methyl)-4-fluorobenzene-1-sulfonamide
L527-0263 Screening compound: N-({3-cyclopropyl-3H-imidazo[4,5-b]pyridin-2-yl}methyl)-4-fluorobenzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L527-0263
N-({3-cyclopropyl-3H-imidazo[4,5-b]pyridin-2-yl}methyl)-4-fluorobenzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L527-0263

Molecular Formula

C16H15FN4O2S (C16 H15 FN4 O2 S)

Compound Name

N-({3-cyclopropyl-3H-imidazo[4,5-b]pyridin-2-yl}methyl)-4-fluorobenzene-1-sulfonamide

IUPAC name

N-({3-cyclopropyl-3H-imidazo[45-b]pyridin-2-yl}methyl)-4-fluorobenzene-1-sulfonamide

SMILES

O=S(c(cc1)ccc1F)(NCc(n1C2CC2)nc2c1nccc2)=O

InChI

InChI=1S/C16H15FN4O2S/c17-11-3-7-13(8-4-11)24(22,23)19-10-15-20-14-2-1-9-18-16(14)21(15)12-5-6-12/h1-4,7-9,12,19H,5-6,10H2

InChI Key

VAPPQWSLFUBFBR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27459775

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

346.39

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.402

Distribution Coefficient, logD

2.305

Water Solubility, LogSw

-2.78

Polar Surface Area

63.716

Acid Dissociation Constant (pKa)

8.00

Base Dissociation Constant (pKb)

3.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

L527-0263 in Drug Discovery

Included in Screening Libraries

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Others

References: we are preparing a list of scientific research reports with L527-0263 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L527-0263?
Check Price and Availability of L527-0263, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L527-0263 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L527-0263
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L527-0263
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L527-0263 available by request