L527-0428 Screening compound: 3-chloro-N-({3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}methyl)-4-methylbenzene-1-sulfonamide

L527-0428 Screening compound: 3-chloro-N-({3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}methyl)-4-methylbenzene-1-sulfonamide
L527-0428 Screening compound: 3-chloro-N-({3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}methyl)-4-methylbenzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L527-0428
3-chloro-N-({3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}methyl)-4-methylbenzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L527-0428

Molecular Formula

C21H18ClFN4O2S (C21 H18 ClFN4 O2 S)

Compound Name

3-chloro-N-({3-[(4-fluorophenyl)methyl]-3H-imidazo[4,5-b]pyridin-2-yl}methyl)-4-methylbenzene-1-sulfonamide

IUPAC name

3-chloro-N-({3-[(4-fluorophenyl)methyl]-3H-imidazo[45-b]pyridin-2-yl}methyl)-4-methylbenzene-1-sulfonamide

SMILES

Cc(ccc(S(NCc(n1Cc(cc2)ccc2F)nc2c1nccc2)(=O)=O)c1)c1Cl

InChI

InChI=1S/C21H18ClFN4O2S/c1-14-4-9-17(11-18(14)22)30(28,29)25-12-20-26-19-3-2-10-24-21(19)27(20)13-15-5-7-16(23)8-6-15/h2-11,25H,12-13H2,1H3

InChI Key

FBJREXFXVWMQFG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27459846

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.92

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.495

Distribution Coefficient, logD

4.313

Water Solubility, LogSw

-4.52

Polar Surface Area

62.808

Acid Dissociation Constant (pKa)

7.68

Base Dissociation Constant (pKb)

4.17

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

L527-0428 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L527-0428 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L527-0428?
Check Price and Availability of L527-0428, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L527-0428 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L527-0428
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L527-0428
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L527-0428 available by request