L528-0021 Screening compound: 2,6-difluoro-N-{7-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-6-yl}benzamide

L528-0021 Screening compound: 2,6-difluoro-N-{7-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-6-yl}benzamide
L528-0021 Screening compound: 2,6-difluoro-N-{7-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-6-yl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L528-0021
2,6-difluoro-N-{7-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-6-yl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L528-0021

Molecular Formula

C14H9F2N3O2S (C14 H9 F2 N3 O2 S)

Compound Name

2,6-difluoro-N-{7-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-6-yl}benzamide

IUPAC name

26-difluoro-N-{7-methyl-5-oxo-5H-[13]thiazolo[32-a]pyrimidin-6-yl}benzamide

SMILES

CC(N=C1SC=CN1C1=O)=C1NC(c(c(F)ccc1)c1F)=O

InChI

InChI=1S/C14H9F2N3O2S/c1-7-11(13(21)19-5-6-22-14(19)17-7)18-12(20)10-8(15)3-2-4-9(10)16/h2-6H,1H3,(H,18,20)

InChI Key

ZWDYMFJXUBYUNR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09245450

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

321.31

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.189

Distribution Coefficient, logD

-1.223

Water Solubility, LogSw

-2.11

Polar Surface Area

48.395

Acid Dissociation Constant (pKa)

4.99

Base Dissociation Constant (pKb)

-1.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

7.10

L528-0021 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L528-0021 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L528-0021?
Check Price and Availability of L528-0021, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L528-0021 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L528-0021
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L528-0021
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L528-0021 available by request