L529-0478 Screening compound: N-(4-CHLOROBENZYL)-N-[(4'-FLUOROBIPHENYL-4-YL)SULFONYL]GLYCINAMIDE

L529-0478 Screening compound: N-(4-CHLOROBENZYL)-N-[(4'-FLUOROBIPHENYL-4-YL)SULFONYL]GLYCINAMIDE
L529-0478 Screening compound: N-(4-CHLOROBENZYL)-N-[(4'-FLUOROBIPHENYL-4-YL)SULFONYL]GLYCINAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L529-0478
N-(4-CHLOROBENZYL)-N-[(4'-FLUOROBIPHENYL-4-YL)SULFONYL]GLYCINAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L529-0478

Molecular Formula

C21H18ClFN2O3S (C21 H18 ClFN2 O3 S)

Compound Name

N-(4-CHLOROBENZYL)-N-[(4'-FLUOROBIPHENYL-4-YL)SULFONYL]GLYCINAMIDE

IUPAC name

n/a

SMILES

O=C(CNS(c(cc1)ccc1-c(cc1)ccc1F)(=O)=O)NCc(cc1)ccc1Cl

InChI

InChI=1S/C21H18ClFN2O3S/c22-18-7-1-15(2-8-18)13-24-21(26)14-25-29(27,28)20-11-5-17(6-12-20)16-3-9-19(23)10-4-16/h1-12,25H,13-14H2,(H,24,26)

InChI Key

BACKTRKOCRQNAK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15129810

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.9

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.628

Distribution Coefficient, logD

4.628

Water Solubility, LogSw

-5.07

Polar Surface Area

66.197

Acid Dissociation Constant (pKa)

10.15

Base Dissociation Constant (pKb)

-3.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

3.00

L529-0478 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L529-0478 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L529-0478?
Check Price and Availability of L529-0478, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L529-0478 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L529-0478
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L529-0478
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L529-0478 available by request