L532-1095 Screening compound: ethyl 2-{4-[5-(cyclopentylamino)-6-(4-ethylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazino}acetate

L532-1095 Screening compound: ethyl 2-{4-[5-(cyclopentylamino)-6-(4-ethylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazino}acetate
L532-1095 Screening compound: ethyl 2-{4-[5-(cyclopentylamino)-6-(4-ethylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazino}acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound L532-1095
ethyl 2-{4-[5-(cyclopentylamino)-6-(4-ethylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazino}acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L532-1095

Molecular Formula

C25H34N6O2S (C25 H34 N6 O2 S)

Compound Name

ethyl 2-{4-[5-(cyclopentylamino)-6-(4-ethylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazino}acetate

IUPAC name

ethyl 2-{4-[5-(cyclopentylamino)-6-(4-ethylphenyl)imidazo[21-b][134]thiadiazol-2-yl]piperazin-1-yl}acetate

SMILES

CCc(cc1)ccc1-c1c(NC2CCCC2)n2nc(N3CCN(CC(OCC)=O)CC3)sc2n1

InChI

InChI=1S/C25H34N6O2S/c1-3-18-9-11-19(12-10-18)22-23(26-20-7-5-6-8-20)31-24(27-22)34-25(28-31)30-15-13-29(14-16-30)17-21(32)33-4-2/h9-12,20,26H,3-8,13-17H2,1-2H3

InChI Key

KIWFTJOLHSIJST-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27459869

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.65

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.884

Distribution Coefficient, logD

4.880

Water Solubility, LogSw

-4.37

Polar Surface Area

58.747

Acid Dissociation Constant (pKa)

23.03

Base Dissociation Constant (pKb)

5.40

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

56.00

L532-1095 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L532-1095 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L532-1095?
Check Price and Availability of L532-1095, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L532-1095 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L532-1095
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L532-1095
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L532-1095 available by request