L532-1848 Screening compound: 2-{4-[5-(TERT-BUTYLAMINO)-6-(4-ETHYLPHENYL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-2-YL]PIPERAZINO}ACETAMIDE

L532-1848 Screening compound: 2-{4-[5-(TERT-BUTYLAMINO)-6-(4-ETHYLPHENYL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-2-YL]PIPERAZINO}ACETAMIDE
L532-1848 Screening compound: 2-{4-[5-(TERT-BUTYLAMINO)-6-(4-ETHYLPHENYL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-2-YL]PIPERAZINO}ACETAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L532-1848
2-{4-[5-(TERT-BUTYLAMINO)-6-(4-ETHYLPHENYL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-2-YL]PIPERAZINO}ACETAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L532-1848

Molecular Formula

C22H31N7OS (C22 H31 N7 OS)

Compound Name

2-{4-[5-(TERT-BUTYLAMINO)-6-(4-ETHYLPHENYL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-2-YL]PIPERAZINO}ACETAMIDE

IUPAC name

2-{4-[5-(tert-butylamino)-6-(4-ethylphenyl)imidazo[21-b][134]thiadiazol-2-yl]piperazin-1-yl}acetamide

SMILES

CCc(cc1)ccc1-c1c(NC(C)(C)C)n2nc(N3CCN(CC(N)=O)CC3)sc2n1

InChI

InChI=1S/C22H31N7OS/c1-5-15-6-8-16(9-7-15)18-19(25-22(2,3)4)29-20(24-18)31-21(26-29)28-12-10-27(11-13-28)14-17(23)30/h6-9,25H,5,10-14H2,1-4H3,(H2,23,30)

InChI Key

QATPDYARGJZMNW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27459924

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

441.6

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.405

Distribution Coefficient, logD

3.393

Water Solubility, LogSw

-3.57

Polar Surface Area

70.980

Acid Dissociation Constant (pKa)

15.42

Base Dissociation Constant (pKb)

5.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

L532-1848 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L532-1848 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L532-1848?
Check Price and Availability of L532-1848, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L532-1848 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L532-1848
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L532-1848
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L532-1848 available by request