L532-1952 Screening compound: 2-{4-[5-(tert-butylamino)-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-1-(pyrrolidin-1-yl)ethan-1-one

L532-1952 Screening compound: 2-{4-[5-(tert-butylamino)-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-1-(pyrrolidin-1-yl)ethan-1-one
L532-1952 Screening compound: 2-{4-[5-(tert-butylamino)-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-1-(pyrrolidin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L532-1952
2-{4-[5-(tert-butylamino)-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-1-(pyrrolidin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L532-1952

Molecular Formula

C24H32FN7OS (C24 H32 FN7 OS)

Compound Name

2-{4-[5-(tert-butylamino)-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-1-(pyrrolidin-1-yl)ethan-1-one

IUPAC name

2-{4-[5-(tert-butylamino)-6-(4-fluorophenyl)imidazo[21-b][134]thiadiazol-2-yl]piperazin-1-yl}-1-(pyrrolidin-1-yl)ethan-1-one

SMILES

CC(C)(C)Nc1c(-c(cc2)ccc2F)nc2sc(N3CCN(CC(N4CCCC4)=O)CC3)nn12

InChI

InChI=1S/C24H32FN7OS/c1-24(2,3)27-21-20(17-6-8-18(25)9-7-17)26-22-32(21)28-23(34-22)31-14-12-29(13-15-31)16-19(33)30-10-4-5-11-30/h6-9,27H,4-5,10-16H2,1-3H3

InChI Key

PINSCSFAEQKMSJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27459937

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.63

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.634

Distribution Coefficient, logD

3.572

Water Solubility, LogSw

-3.77

Polar Surface Area

54.079

Acid Dissociation Constant (pKa)

21.97

Base Dissociation Constant (pKb)

6.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

54.20

L532-1952 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L532-1952 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L532-1952?
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What is the minimum amount of L532-1952 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L532-1952
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L532-1952
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L532-1952 available by request