L532-2314 Screening compound: N-tert-butyl-2-{4-[(4-fluorophenyl)methyl]piperazin-1-yl}-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-amine

L532-2314 Screening compound: N-tert-butyl-2-{4-[(4-fluorophenyl)methyl]piperazin-1-yl}-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-amine
L532-2314 Screening compound: N-tert-butyl-2-{4-[(4-fluorophenyl)methyl]piperazin-1-yl}-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound L532-2314
N-tert-butyl-2-{4-[(4-fluorophenyl)methyl]piperazin-1-yl}-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L532-2314

Molecular Formula

C25H29FN6S (C25 H29 FN6 S)

Compound Name

N-tert-butyl-2-{4-[(4-fluorophenyl)methyl]piperazin-1-yl}-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-amine

IUPAC name

N-tert-butyl-2-{4-[(4-fluorophenyl)methyl]piperazin-1-yl}-6-phenylimidazo[21-b][134]thiadiazol-5-amine

SMILES

CC(C)(C)Nc1c(-c2ccccc2)nc2sc(N3CCN(Cc(cc4)ccc4F)CC3)nn12

InChI

InChI=1S/C25H29FN6S/c1-25(2,3)28-22-21(19-7-5-4-6-8-19)27-23-32(22)29-24(33-23)31-15-13-30(14-16-31)17-18-9-11-20(26)12-10-18/h4-12,28H,13-17H2,1-3H3

InChI Key

ZPWFSPVLRGJKAD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27459982

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.61

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.194

Distribution Coefficient, logD

5.123

Water Solubility, LogSw

-5.19

Polar Surface Area

37.320

Acid Dissociation Constant (pKa)

21.97

Base Dissociation Constant (pKb)

6.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.00

L532-2314 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with L532-2314 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L532-2314?
Check Price and Availability of L532-2314, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L532-2314 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L532-2314
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L532-2314
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L532-2314 available by request