L532-2345 Screening compound: 2-{4-[5-(tert-butylamino)-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-1-(4-methylpiperidin-1-yl)ethan-1-one

L532-2345 Screening compound: 2-{4-[5-(tert-butylamino)-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-1-(4-methylpiperidin-1-yl)ethan-1-one
L532-2345 Screening compound: 2-{4-[5-(tert-butylamino)-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-1-(4-methylpiperidin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L532-2345
2-{4-[5-(tert-butylamino)-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-1-(4-methylpiperidin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L532-2345

Molecular Formula

C26H37N7OS (C26 H37 N7 OS)

Compound Name

2-{4-[5-(tert-butylamino)-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-1-(4-methylpiperidin-1-yl)ethan-1-one

IUPAC name

2-{4-[5-(tert-butylamino)-6-phenylimidazo[21-b][134]thiadiazol-2-yl]piperazin-1-yl}-1-(4-methylpiperidin-1-yl)ethan-1-one

SMILES

CC(CC1)CCN1C(CN(CC1)CCN1c(s1)nn2c1nc(-c1ccccc1)c2NC(C)(C)C)=O

InChI

InChI=1S/C26H37N7OS/c1-19-10-12-31(13-11-19)21(34)18-30-14-16-32(17-15-30)25-29-33-23(28-26(2,3)4)22(27-24(33)35-25)20-8-6-5-7-9-20/h5-9,19,28H,10-18H2,1-4H3

InChI Key

WZBWPVDRUHYYMX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27459995

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

495.69

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.049

Distribution Coefficient, logD

4.036

Water Solubility, LogSw

-3.91

Polar Surface Area

53.713

Acid Dissociation Constant (pKa)

21.97

Base Dissociation Constant (pKb)

5.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

57.70

L532-2345 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L532-2345 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L532-2345?
Check Price and Availability of L532-2345, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L532-2345 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L532-2345
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L532-2345
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L532-2345 available by request