L537-0094 Screening compound: 2-(4-{5-[1-cyclohexyl-4-(4-methylphenyl)-1H-imidazol-5-yl]furan-2-carbonyl}piperazin-1-yl)pyrimidine

L537-0094 Screening compound: 2-(4-{5-[1-cyclohexyl-4-(4-methylphenyl)-1H-imidazol-5-yl]furan-2-carbonyl}piperazin-1-yl)pyrimidine
L537-0094 Screening compound: 2-(4-{5-[1-cyclohexyl-4-(4-methylphenyl)-1H-imidazol-5-yl]furan-2-carbonyl}piperazin-1-yl)pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L537-0094
2-(4-{5-[1-cyclohexyl-4-(4-methylphenyl)-1H-imidazol-5-yl]furan-2-carbonyl}piperazin-1-yl)pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L537-0094

Molecular Formula

C29H32N6O2 (C29 H32 N6 O2)

Compound Name

2-(4-{5-[1-cyclohexyl-4-(4-methylphenyl)-1H-imidazol-5-yl]furan-2-carbonyl}piperazin-1-yl)pyrimidine

IUPAC name

2-(4-{5-[1-cyclohexyl-4-(4-methylphenyl)-1H-imidazol-5-yl]furan-2-carbonyl}piperazin-1-yl)pyrimidine

SMILES

Cc(cc1)ccc1-c1c(-c2ccc(C(N(CC3)CCN3c3ncccn3)=O)o2)n(C2CCCCC2)cn1

InChI

InChI=1S/C29H32N6O2/c1-21-8-10-22(11-9-21)26-27(35(20-32-26)23-6-3-2-4-7-23)24-12-13-25(37-24)28(36)33-16-18-34(19-17-33)29-30-14-5-15-31-29/h5,8-15,20,23H,2-4,6-7,16-19H2,1H3

InChI Key

DMJKCKFFOZKQGT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27460385

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.61

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.397

Distribution Coefficient, logD

5.360

Water Solubility, LogSw

-5.32

Polar Surface Area

57.424

Acid Dissociation Constant (pKa)

21.08

Base Dissociation Constant (pKb)

6.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.90

L537-0094 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Regenerative Medicine Focused Library (23016 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L537-0094 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L537-0094?
Check Price and Availability of L537-0094, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L537-0094 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L537-0094
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L537-0094
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L537-0094 available by request