L537-0405 Screening compound: methyl 2-{5-[1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]furan-2-amido}benzoate

L537-0405 Screening compound: methyl 2-{5-[1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]furan-2-amido}benzoate
L537-0405 Screening compound: methyl 2-{5-[1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]furan-2-amido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L537-0405
methyl 2-{5-[1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]furan-2-amido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L537-0405

Molecular Formula

C27H24FN3O4 (C27 H24 FN3 O4)

Compound Name

methyl 2-{5-[1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]furan-2-amido}benzoate

IUPAC name

methyl 2-{5-[1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]furan-2-amido}benzoate

SMILES

COC(c(cccc1)c1NC(c1ccc(-c2c(-c(cc3)ccc3F)ncn2C2CCCC2)o1)=O)=O

InChI

InChI=1S/C27H24FN3O4/c1-34-27(33)20-8-4-5-9-21(20)30-26(32)23-15-14-22(35-23)25-24(17-10-12-18(28)13-11-17)29-16-31(25)19-6-2-3-7-19/h4-5,8-16,19H,2-3,6-7H2,1H3,(H,30,32)

InChI Key

KDJJXBPORVAUEF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27460444

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

473.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.365

Distribution Coefficient, logD

5.312

Water Solubility, LogSw

-5.35

Polar Surface Area

63.087

Acid Dissociation Constant (pKa)

8.30

Base Dissociation Constant (pKb)

5.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

L537-0405 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with L537-0405 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L537-0405?
Check Price and Availability of L537-0405, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L537-0405 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L537-0405
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L537-0405
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L537-0405 available by request