L537-0559 Screening compound: 5-[1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-N-{[4-(propan-2-yloxy)phenyl]methyl}furan-2-carboxamide

L537-0559 Screening compound: 5-[1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-N-{[4-(propan-2-yloxy)phenyl]methyl}furan-2-carboxamide
L537-0559 Screening compound: 5-[1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-N-{[4-(propan-2-yloxy)phenyl]methyl}furan-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L537-0559
5-[1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-N-{[4-(propan-2-yloxy)phenyl]methyl}furan-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L537-0559

Molecular Formula

C29H30FN3O3 (C29 H30 FN3 O3)

Compound Name

5-[1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-N-{[4-(propan-2-yloxy)phenyl]methyl}furan-2-carboxamide

IUPAC name

5-[1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-N-{[4-(propan-2-yloxy)phenyl]methyl}furan-2-carboxamide

SMILES

CC(C)Oc1ccc(CNC(c2ccc(-c3c(-c(cc4)ccc4F)ncn3C3CCCC3)o2)=O)cc1

InChI

InChI=1S/C29H30FN3O3/c1-19(2)35-24-13-7-20(8-14-24)17-31-29(34)26-16-15-25(36-26)28-27(21-9-11-22(30)12-10-21)32-18-33(28)23-5-3-4-6-23/h7-16,18-19,23H,3-6,17H2,1-2H3,(H,31,34)

InChI Key

BOFLKSODTGESNT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27460539

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

487.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.658

Distribution Coefficient, logD

5.657

Water Solubility, LogSw

-5.43

Polar Surface Area

50.735

Acid Dissociation Constant (pKa)

13.70

Base Dissociation Constant (pKb)

5.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.00

L537-0559 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

MCL1 Targeted Library (12200 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic

References: we are preparing a list of scientific research reports with L537-0559 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L537-0559?
Check Price and Availability of L537-0559, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L537-0559 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L537-0559
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L537-0559
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L537-0559 available by request