L537-1081 Screening compound: 1-cyclohexyl-4-(4-fluorophenyl)-5-[5-(pyrrolidine-1-carbonyl)furan-2-yl]-1H-imidazole

L537-1081 Screening compound: 1-cyclohexyl-4-(4-fluorophenyl)-5-[5-(pyrrolidine-1-carbonyl)furan-2-yl]-1H-imidazole
L537-1081 Screening compound: 1-cyclohexyl-4-(4-fluorophenyl)-5-[5-(pyrrolidine-1-carbonyl)furan-2-yl]-1H-imidazole alternative view

Chemical Structure Depiction of ChemDiv screening compound L537-1081
1-cyclohexyl-4-(4-fluorophenyl)-5-[5-(pyrrolidine-1-carbonyl)furan-2-yl]-1H-imidazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L537-1081

Molecular Formula

C24H26FN3O2 (C24 H26 FN3 O2)

Compound Name

1-cyclohexyl-4-(4-fluorophenyl)-5-[5-(pyrrolidine-1-carbonyl)furan-2-yl]-1H-imidazole

IUPAC name

1-cyclohexyl-4-(4-fluorophenyl)-5-[5-(pyrrolidine-1-carbonyl)furan-2-yl]-1H-imidazole

SMILES

O=C(c1ccc(-c2c(-c(cc3)ccc3F)ncn2C2CCCCC2)o1)N1CCCC1

InChI

InChI=1S/C24H26FN3O2/c25-18-10-8-17(9-11-18)22-23(28(16-26-22)19-6-2-1-3-7-19)20-12-13-21(30-20)24(29)27-14-4-5-15-27/h8-13,16,19H,1-7,14-15H2

InChI Key

RXMOONWCUXZQQL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27460601

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.916

Distribution Coefficient, logD

4.914

Water Solubility, LogSw

-4.83

Polar Surface Area

36.168

Acid Dissociation Constant (pKa)

22.86

Base Dissociation Constant (pKb)

5.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

L537-1081 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L537-1081 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L537-1081?
Check Price and Availability of L537-1081, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L537-1081 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L537-1081
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L537-1081
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L537-1081 available by request