L537-1106 Screening compound: 1-{5-[1-cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]furan-2-carbonyl}-4-(pyridin-2-yl)piperazine

L537-1106 Screening compound: 1-{5-[1-cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]furan-2-carbonyl}-4-(pyridin-2-yl)piperazine
L537-1106 Screening compound: 1-{5-[1-cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]furan-2-carbonyl}-4-(pyridin-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L537-1106
1-{5-[1-cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]furan-2-carbonyl}-4-(pyridin-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L537-1106

Molecular Formula

C29H30FN5O2 (C29 H30 FN5 O2)

Compound Name

1-{5-[1-cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]furan-2-carbonyl}-4-(pyridin-2-yl)piperazine

IUPAC name

1-{5-[1-cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]furan-2-carbonyl}-4-(pyridin-2-yl)piperazine

SMILES

O=C(c1ccc(-c2c(-c(cc3)ccc3F)ncn2C2CCCCC2)o1)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C29H30FN5O2/c30-22-11-9-21(10-12-22)27-28(35(20-32-27)23-6-2-1-3-7-23)24-13-14-25(37-24)29(36)34-18-16-33(17-19-34)26-8-4-5-15-31-26/h4-5,8-15,20,23H,1-3,6-7,16-19H2

InChI Key

BAJMKAVAUICOFL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27460621

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.59

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.506

Distribution Coefficient, logD

5.497

Water Solubility, LogSw

-5.74

Polar Surface Area

47.573

Acid Dissociation Constant (pKa)

22.86

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.50

L537-1106 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with L537-1106 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L537-1106?
Check Price and Availability of L537-1106, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L537-1106 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L537-1106
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L537-1106
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L537-1106 available by request