L553-0380 Screening compound: N-[(4-chlorophenyl)methyl]-3-[3-(4-fluorophenyl)-4-(piperidin-1-yl)-[1,2]oxazolo[5,4-d]pyrimidin-6-yl]propanamide

L553-0380 Screening compound: N-[(4-chlorophenyl)methyl]-3-[3-(4-fluorophenyl)-4-(piperidin-1-yl)-[1,2]oxazolo[5,4-d]pyrimidin-6-yl]propanamide
L553-0380 Screening compound: N-[(4-chlorophenyl)methyl]-3-[3-(4-fluorophenyl)-4-(piperidin-1-yl)-[1,2]oxazolo[5,4-d]pyrimidin-6-yl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L553-0380
N-[(4-chlorophenyl)methyl]-3-[3-(4-fluorophenyl)-4-(piperidin-1-yl)-[1,2]oxazolo[5,4-d]pyrimidin-6-yl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L553-0380

Molecular Formula

C26H25ClFN5O2 (C26 H25 ClFN5 O2)

Compound Name

N-[(4-chlorophenyl)methyl]-3-[3-(4-fluorophenyl)-4-(piperidin-1-yl)-[1,2]oxazolo[5,4-d]pyrimidin-6-yl]propanamide

IUPAC name

N-[(4-chlorophenyl)methyl]-3-[3-(4-fluorophenyl)-4-(piperidin-1-yl)-[12]oxazolo[54-d]pyrimidin-6-yl]propanamide

SMILES

O=C(CCc1nc(N2CCCCC2)c(c(-c(cc2)ccc2F)no2)c2n1)NCc(cc1)ccc1Cl

InChI

InChI=1S/C26H25ClFN5O2/c27-19-8-4-17(5-9-19)16-29-22(34)13-12-21-30-25(33-14-2-1-3-15-33)23-24(32-35-26(23)31-21)18-6-10-20(28)11-7-18/h4-11H,1-3,12-16H2,(H,29,34)

InChI Key

RUSRZDKVIFDMDW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27461200

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.97

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.237

Distribution Coefficient, logD

5.237

Water Solubility, LogSw

-5.87

Polar Surface Area

69.486

Acid Dissociation Constant (pKa)

12.45

Base Dissociation Constant (pKb)

3.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.80

L553-0380 in Drug Discovery

Included in Screening Libraries

MCL1 Targeted Library (12200 compounds)

Targeted Diversity Library (40567 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L553-0380 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L553-0380?
Check Price and Availability of L553-0380, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L553-0380 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L553-0380
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L553-0380
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L553-0380 available by request