L555-0496 Screening compound: N-(4-fluorophenyl)-5,6-dimethyl-7-phenyl-4-(piperidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine-2-carboxamide

L555-0496 Screening compound: N-(4-fluorophenyl)-5,6-dimethyl-7-phenyl-4-(piperidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine-2-carboxamide
L555-0496 Screening compound: N-(4-fluorophenyl)-5,6-dimethyl-7-phenyl-4-(piperidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L555-0496
N-(4-fluorophenyl)-5,6-dimethyl-7-phenyl-4-(piperidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L555-0496

Molecular Formula

C26H26FN5O (C26 H26 FN5 O)

Compound Name

N-(4-fluorophenyl)-5,6-dimethyl-7-phenyl-4-(piperidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine-2-carboxamide

IUPAC name

N-(4-fluorophenyl)-56-dimethyl-7-phenyl-4-(piperidin-1-yl)-7H-pyrrolo[23-d]pyrimidine-2-carboxamide

SMILES

Cc(c1c(N2CCCCC2)nc(C(Nc(cc2)ccc2F)=O)nc11)c(C)n1-c1ccccc1

InChI

InChI=1S/C26H26FN5O/c1-17-18(2)32(21-9-5-3-6-10-21)25-22(17)24(31-15-7-4-8-16-31)29-23(30-25)26(33)28-20-13-11-19(27)12-14-20/h3,5-6,9-14H,4,7-8,15-16H2,1-2H3,(H,28,33)

InChI Key

ROHUEWYHBZKAQM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27461607

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.52

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.782

Distribution Coefficient, logD

5.782

Water Solubility, LogSw

-5.69

Polar Surface Area

48.089

Acid Dissociation Constant (pKa)

11.08

Base Dissociation Constant (pKb)

4.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.90

L555-0496 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L555-0496 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L555-0496?
Check Price and Availability of L555-0496, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L555-0496 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L555-0496
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L555-0496
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L555-0496 available by request