L557-0148 Screening compound: 3-[5-chloro-2-(pyridin-4-yl)-1H-indol-3-yl]-1-(3-fluoro-4-methylphenyl)urea

L557-0148 Screening compound: 3-[5-chloro-2-(pyridin-4-yl)-1H-indol-3-yl]-1-(3-fluoro-4-methylphenyl)urea
L557-0148 Screening compound: 3-[5-chloro-2-(pyridin-4-yl)-1H-indol-3-yl]-1-(3-fluoro-4-methylphenyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L557-0148
3-[5-chloro-2-(pyridin-4-yl)-1H-indol-3-yl]-1-(3-fluoro-4-methylphenyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L557-0148

Molecular Formula

C21H16ClFN4O (C21 H16 ClFN4 O)

Compound Name

3-[5-chloro-2-(pyridin-4-yl)-1H-indol-3-yl]-1-(3-fluoro-4-methylphenyl)urea

IUPAC name

3-[5-chloro-2-(pyridin-4-yl)-1H-indol-3-yl]-1-(3-fluoro-4-methylphenyl)urea

SMILES

Cc(ccc(NC(Nc1c(-c2ccncc2)[nH]c(cc2)c1cc2Cl)=O)c1)c1F

InChI

InChI=1S/C21H16ClFN4O/c1-12-2-4-15(11-17(12)23)25-21(28)27-20-16-10-14(22)3-5-18(16)26-19(20)13-6-8-24-9-7-13/h2-11,26H,1H3,(H2,25,27,28)

InChI Key

LXMNGASXPAPYOK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15130420

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.84

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.938

Distribution Coefficient, logD

4.937

Water Solubility, LogSw

-5.06

Polar Surface Area

50.422

Acid Dissociation Constant (pKa)

12.10

Base Dissociation Constant (pKb)

4.57

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.80

L557-0148 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
Agro:
  • Agro
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L557-0148 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L557-0148?
Check Price and Availability of L557-0148, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L557-0148 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L557-0148
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L557-0148
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L557-0148 available by request