L557-0232 Screening compound: 1-(4-bromophenyl)-3-[5-fluoro-2-(pyridin-4-yl)-1H-indol-3-yl]urea

L557-0232 Screening compound: 1-(4-bromophenyl)-3-[5-fluoro-2-(pyridin-4-yl)-1H-indol-3-yl]urea
L557-0232 Screening compound: 1-(4-bromophenyl)-3-[5-fluoro-2-(pyridin-4-yl)-1H-indol-3-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L557-0232
1-(4-bromophenyl)-3-[5-fluoro-2-(pyridin-4-yl)-1H-indol-3-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L557-0232

Molecular Formula

C20H14BrFN4O (C20 H14 BrFN4 O)

Compound Name

1-(4-bromophenyl)-3-[5-fluoro-2-(pyridin-4-yl)-1H-indol-3-yl]urea

IUPAC name

1-(4-bromophenyl)-3-[5-fluoro-2-(pyridin-4-yl)-1H-indol-3-yl]urea

SMILES

O=C(Nc1c(-c2ccncc2)[nH]c(cc2)c1cc2F)Nc(cc1)ccc1Br

InChI

InChI=1S/C20H14BrFN4O/c21-13-1-4-15(5-2-13)24-20(27)26-19-16-11-14(22)3-6-17(16)25-18(19)12-7-9-23-10-8-12/h1-11,25H,(H2,24,26,27)

InChI Key

DKMYLWRDBVMOQE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15130438

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

425.26

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.511

Distribution Coefficient, logD

4.510

Water Solubility, LogSw

-4.31

Polar Surface Area

50.422

Acid Dissociation Constant (pKa)

12.42

Base Dissociation Constant (pKb)

4.57

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

L557-0232 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

CNS Targets (44014 compounds)

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L557-0232 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L557-0232?
Check Price and Availability of L557-0232, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L557-0232 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L557-0232
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L557-0232
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L557-0232 available by request