L557-0244 Screening compound: ethyl 3-[({[5-fluoro-2-(4-pyridyl)-1H-indol-3-yl]amino}carbonyl)amino]-3-phenylpropanoate

L557-0244 Screening compound: ethyl 3-[({[5-fluoro-2-(4-pyridyl)-1H-indol-3-yl]amino}carbonyl)amino]-3-phenylpropanoate
L557-0244 Screening compound: ethyl 3-[({[5-fluoro-2-(4-pyridyl)-1H-indol-3-yl]amino}carbonyl)amino]-3-phenylpropanoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L557-0244
ethyl 3-[({[5-fluoro-2-(4-pyridyl)-1H-indol-3-yl]amino}carbonyl)amino]-3-phenylpropanoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L557-0244

Molecular Formula

C25H23FN4O3 (C25 H23 FN4 O3)

Compound Name

ethyl 3-[({[5-fluoro-2-(4-pyridyl)-1H-indol-3-yl]amino}carbonyl)amino]-3-phenylpropanoate

IUPAC name

ethyl 3-({[5-fluoro-2-(pyridin-4-yl)-1H-indol-3-yl]carbamoyl}amino)-3-phenylpropanoate

SMILES

CCOC(CC(c1ccccc1)NC(Nc1c(-c2ccncc2)[nH]c(cc2)c1cc2F)=O)=O

InChI

InChI=1S/C25H23FN4O3/c1-2-33-22(31)15-21(16-6-4-3-5-7-16)29-25(32)30-24-19-14-18(26)8-9-20(19)28-23(24)17-10-12-27-13-11-17/h3-14,21,28H,2,15H2,1H3,(H2,29,30,32)

InChI Key

BXWMBPGEFIRPMS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27461637

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.423

Distribution Coefficient, logD

3.423

Water Solubility, LogSw

-3.69

Polar Surface Area

71.533

Acid Dissociation Constant (pKa)

14.61

Base Dissociation Constant (pKb)

4.57

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

16.00

L557-0244 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Indole Derivatives (10091 compounds)

Integrin Receptors Targeted library (1715 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Others
  • Kinases

References: we are preparing a list of scientific research reports with L557-0244 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L557-0244?
Check Price and Availability of L557-0244, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L557-0244 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L557-0244
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L557-0244
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L557-0244 available by request