L557-0248 Screening compound: methyl 4-({[5-fluoro-2-(pyridin-4-yl)-1H-indol-3-yl]carbamoyl}amino)benzoate

L557-0248 Screening compound: methyl 4-({[5-fluoro-2-(pyridin-4-yl)-1H-indol-3-yl]carbamoyl}amino)benzoate
L557-0248 Screening compound: methyl 4-({[5-fluoro-2-(pyridin-4-yl)-1H-indol-3-yl]carbamoyl}amino)benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L557-0248
methyl 4-({[5-fluoro-2-(pyridin-4-yl)-1H-indol-3-yl]carbamoyl}amino)benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L557-0248

Molecular Formula

C22H17FN4O3 (C22 H17 FN4 O3)

Compound Name

methyl 4-({[5-fluoro-2-(pyridin-4-yl)-1H-indol-3-yl]carbamoyl}amino)benzoate

IUPAC name

methyl 4-({[5-fluoro-2-(pyridin-4-yl)-1H-indol-3-yl]carbamoyl}amino)benzoate

SMILES

COC(c(cc1)ccc1NC(Nc1c(-c2ccncc2)[nH]c(cc2)c1cc2F)=O)=O

InChI

InChI=1S/C22H17FN4O3/c1-30-21(28)14-2-5-16(6-3-14)25-22(29)27-20-17-12-15(23)4-7-18(17)26-19(20)13-8-10-24-11-9-13/h2-12,26H,1H3,(H2,25,27,29)

InChI Key

JCHMIFKRILDRRP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15130440

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.767

Distribution Coefficient, logD

3.767

Water Solubility, LogSw

-4.18

Polar Surface Area

71.596

Acid Dissociation Constant (pKa)

12.52

Base Dissociation Constant (pKb)

4.57

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.50

L557-0248 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Antiviral Library (67538 compounds)

Indole Derivatives (10091 compounds)

Integrin Receptors Targeted library (1715 compounds)

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Immune system
  • Cancer
  • Endocrine
Agro:
  • Agro
Structure:
  • Cyclic compounds
Targets:
  • Others
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L557-0248 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L557-0248?
Check Price and Availability of L557-0248, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L557-0248 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L557-0248
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L557-0248
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L557-0248 available by request