L560-0773 Screening compound: N~1~-[2-(1-azepanyl)ethyl]-2-[6,12-dioxo-6,6a,7,8,9,10-hexahydropyrido[2,1-c][1,4]benzodiazepin-5(12H)-yl]acetamide

L560-0773 Screening compound: N~1~-[2-(1-azepanyl)ethyl]-2-[6,12-dioxo-6,6a,7,8,9,10-hexahydropyrido[2,1-c][1,4]benzodiazepin-5(12H)-yl]acetamide
L560-0773 Screening compound: N~1~-[2-(1-azepanyl)ethyl]-2-[6,12-dioxo-6,6a,7,8,9,10-hexahydropyrido[2,1-c][1,4]benzodiazepin-5(12H)-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L560-0773
N~1~-[2-(1-azepanyl)ethyl]-2-[6,12-dioxo-6,6a,7,8,9,10-hexahydropyrido[2,1-c][1,4]benzodiazepin-5(12H)-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L560-0773

Molecular Formula

C23H32N4O3 (C23 H32 N4 O3)

Compound Name

N~1~-[2-(1-azepanyl)ethyl]-2-[6,12-dioxo-6,6a,7,8,9,10-hexahydropyrido[2,1-c][1,4]benzodiazepin-5(12H)-yl]acetamide

IUPAC name

N-[2-(azepan-1-yl)ethyl]-2-{210-dioxo-19-diazatricyclo[9.4.0.0^{38}]pentadeca-3(8)46-trien-9-yl}acetamide

SMILES

O=C(CN(c(cccc1)c1C(N1C2CCCC1)=O)C2=O)NCCN1CCCCCC1

InChI

InChI=1S/C23H32N4O3/c28-21(24-12-16-25-13-6-1-2-7-14-25)17-27-19-10-4-3-9-18(19)22(29)26-15-8-5-11-20(26)23(27)30/h3-4,9-10,20H,1-2,5-8,11-17H2,(H,24,28)/t20-/m0/s1

InChI Key

DQHTWESHWRWRRX-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD08336714

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.53

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.191

Distribution Coefficient, logD

-0.294

Water Solubility, LogSw

-2.45

Polar Surface Area

60.534

Acid Dissociation Constant (pKa)

13.88

Base Dissociation Constant (pKb)

8.87

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

60.87

L560-0773 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Protein-Protein Interaction Library (218420 compounds)

Soluble Diversity Library (15920 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Epigenetics Focused Set (26518 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cancer
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L560-0773 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L560-0773?
Check Price and Availability of L560-0773, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L560-0773 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L560-0773
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L560-0773
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L560-0773 available by request