L563-0386 Screening compound: N-[(4-chlorophenyl)methyl]-4-[2-(3-methoxyphenoxy)pyrimidin-5-yl]benzamide
Chemical Structure Depiction of ChemDiv screening compound L563-0386
N-[(4-chlorophenyl)methyl]-4-[2-(3-methoxyphenoxy)pyrimidin-5-yl]benzamide
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
L563-0386
Molecular Formula
C25H20ClN3O3 (C25 H20 ClN3 O3)
Compound Name
N-[(4-chlorophenyl)methyl]-4-[2-(3-methoxyphenoxy)pyrimidin-5-yl]benzamide
IUPAC name
N-[(4-chlorophenyl)methyl]-4-[2-(3-methoxyphenoxy)pyrimidin-5-yl]benzamide
SMILES
COc1cccc(Oc(nc2)ncc2-c(cc2)ccc2C(NCc(cc2)ccc2Cl)=O)c1
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
445.9
Hydrogen Bond Acceptors Count
6.00
Hydrogen Bond Donors Count
1.00
Rotatable Bond Count
8.00
Number of Nitrogen and Oxygen Atoms
6
Partition Coefficient, logP
5.108
Distribution Coefficient, logD
5.108
Water Solubility, LogSw
-5.75
Polar Surface Area
58.087
Acid Dissociation Constant (pKa)
11.36
Base Dissociation Constant (pKb)
-0.34
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
8.00
L563-0386 in Drug Discovery
Included in Screening Libraries
Angiogenesis library (14822 compounds)
Autophagy-Targeted Library (4564 compounds)
Akt-Targeted Library (14764 compounds)
Histone Deacetylases (HDAC) Targeted Library (9760 compounds)
Included in 1.7M Stock Database
- Cancer
- Infections
- Cancer
- Digestive system
- Respiratory tract
- Nervous system
- Male
- Female
- Cardiovascular
- Skin
- Metabolic
- Immune system
- Digestive system
- Respiratory tract
- Male
- Female
- Hemic and lymphatic
- Skin
- Cancer
- Nervous system
- Hemic and lymphatic
- Endocrine
- Immune system
- Kinases
- Epigenetic
References: we are preparing a list of scientific research reports with L563-0386 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)