L566-0377 Screening compound: N~1~-(3,4-dihydro-2H-chromen-3-yl)-N~3~-(4-fluorobenzyl)-3-methyltetrahydro-1,3(2H)-pyridinedicarboxamide

L566-0377 Screening compound: N~1~-(3,4-dihydro-2H-chromen-3-yl)-N~3~-(4-fluorobenzyl)-3-methyltetrahydro-1,3(2H)-pyridinedicarboxamide
L566-0377 Screening compound: N~1~-(3,4-dihydro-2H-chromen-3-yl)-N~3~-(4-fluorobenzyl)-3-methyltetrahydro-1,3(2H)-pyridinedicarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L566-0377
N~1~-(3,4-dihydro-2H-chromen-3-yl)-N~3~-(4-fluorobenzyl)-3-methyltetrahydro-1,3(2H)-pyridinedicarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L566-0377

Molecular Formula

C24H28FN3O3 (C24 H28 FN3 O3)

Compound Name

N~1~-(3,4-dihydro-2H-chromen-3-yl)-N~3~-(4-fluorobenzyl)-3-methyltetrahydro-1,3(2H)-pyridinedicarboxamide

IUPAC name

n/a

SMILES

CC(CCC1)(CN1C(NC(C1)COc2c1cccc2)=O)C(NCc(cc1)ccc1F)=O

InChI

InChI=1S/C24H28FN3O3/c1-24(22(29)26-14-17-7-9-19(25)10-8-17)11-4-12-28(16-24)23(30)27-20-13-18-5-2-3-6-21(18)31-15-20/h2-3,5-10,20H,4,11-16H2,1H3,(H,26,29)(H,27,30)

InChI Key

FCGAQFODMWDPLH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27642322

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

425.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.742

Distribution Coefficient, logD

3.742

Water Solubility, LogSw

-3.89

Polar Surface Area

59.280

Acid Dissociation Constant (pKa)

11.82

Base Dissociation Constant (pKb)

1.23

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

41.70

L566-0377 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L566-0377 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L566-0377?
Check Price and Availability of L566-0377, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L566-0377 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L566-0377
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L566-0377
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L566-0377 available by request