L575-0144 Screening compound: N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-[1-methyl-3-(pyrrolidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-4-oxobutanamide

Chemical Structure Depiction of ChemDiv screening compound L575-0144
N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-[1-methyl-3-(pyrrolidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-4-oxobutanamide

Available from 1 mg

Formats:

Glass Vials (4ml Glass Vials VWR #97047-678)
96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

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Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L575-0144

Molecular Formula

C₂₄H₂₉N₅O₅ (C24 H29 N5 O5)

Compound Name

N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-[1-methyl-3-(pyrrolidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-4-oxobutanamide

IUPAC name

N-[(2H-13-benzodioxol-5-yl)methyl]-4-[1-methyl-3-(pyrrolidine-1-carbonyl)-1H4H5H6H7H-pyrazolo[43-c]pyridin-5-yl]-4-oxobutanamide

SMILES

Cn1nc(C(N2CCCC2)=O)c(C2)c1CCN2C(CCC(NCc(cc1)cc2c1OCO2)=O)=O

InChI

InChI=1S/C24H29N5O5/c1-27-18-8-11-29(14-17(18)23(26-27)24(32)28-9-2-3-10-28)22(31)7-6-21(30)25-13-16-4-5-19-20(12-16)34-15-33-19/h4-5,12H,2-3,6-11,13-15H2,1H3,(H,25,30)

InChI Key

NJFXFMCSTOXYFK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27463468

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.52

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

Partition Coefficient, logP

0.289

Distribution Coefficient, logD

0.288

Water Solubility, LogSw

-2.07

Polar Surface Area

89.640

Acid Dissociation Constant (pK_a)

14.45

Base Dissociation Constant (pK_b)

3.55

Number of Chiral Centers

0.00

Percent sp³ carbon bonding

50.00

L575-0144 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:

Cancer
Infections
Cancer
Musculoskeletal
Digestive system
Nervous system
Cardiovascular
Skin
Metabolic
Endocrine
Immune system
Cancer
Digestive system
Respiratory tract
Male
Female
Hemic and lymphatic
Immune system
Musculoskeletal
Digestive system
Hemic and lymphatic
Cardiovascular
Skin
wounds
Cancer
Digestive system
Respiratory tract
Nervous system
Eye
Cardiovascular

Targets:

Proteases
GPCR

Mechanism of action:

PPI modulators
Receptor's ligands

Structure:

Mimetics

References: we are preparing a list of scientific research reports with L575-0144 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L575-0144?
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What is the minimum amount of L575-0144 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.

Delivery options for L575-0144
ChemDiv sends parcels with Express services (UPS, WC).

1–2 days for small orders
2–4 weeks for large selections

Delivery formats for L575-0144

0.5–50 mg of dry powder sample in single glass vials, custom vials
DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L575-0144 available by request