L575-0187 Screening compound: N-[2-(1H-indol-3-yl)ethyl]-4-[1-methyl-3-(pyrrolidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-4-oxobutanamide
Chemical Structure Depiction of ChemDiv screening compound L575-0187
N-[2-(1H-indol-3-yl)ethyl]-4-[1-methyl-3-(pyrrolidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-4-oxobutanamide
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
L575-0187
Molecular Formula
C26H32N6O3 (C26 H32 N6 O3)
Compound Name
N-[2-(1H-indol-3-yl)ethyl]-4-[1-methyl-3-(pyrrolidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-4-oxobutanamide
IUPAC name
N-[2-(1H-indol-3-yl)ethyl]-4-[1-methyl-3-(pyrrolidine-1-carbonyl)-1H4H5H6H7H-pyrazolo[43-c]pyridin-5-yl]-4-oxobutanamide
SMILES
Cn1nc(C(N2CCCC2)=O)c(C2)c1CCN2C(CCC(NCCc1c[nH]c2c1cccc2)=O)=O
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
476.58
Hydrogen Bond Acceptors Count
7.00
Hydrogen Bond Donors Count
2.00
Rotatable Bond Count
10.00
Number of Nitrogen and Oxygen Atoms
9
Partition Coefficient, logP
0.501
Distribution Coefficient, logD
0.501
Water Solubility, LogSw
-2.09
Polar Surface Area
82.237
Acid Dissociation Constant (pKa)
14.24
Base Dissociation Constant (pKb)
3.55
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
46.20
L575-0187 in Drug Discovery
Included in Screening Libraries
3D-Diversity Natural-Product-Like Library (18102 compounds)
Anticancer Library (62698 compounds)
300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)
Cysteine Proteases Inhibitors Library (7839 compounds)
Hsp90-Targeted Library (11355 compounds)
Indole Derivatives (10091 compounds)
MCL1 Targeted Library (12200 compounds)
PPI Inhibitors Tripeptide Mimetics (23972 compounds)
SmartTM Library (51161 compounds)
Targeted Diversity Library (40567 compounds)
Included in 1.7M Stock Database
- 3D
- Cyclic compounds
- Mimetics
- Cancer
- Infections
- Cancer
- Musculoskeletal
- Digestive system
- Nervous system
- Cardiovascular
- Skin
- Metabolic
- Endocrine
- Immune system
- Cancer
- Digestive system
- Respiratory tract
- Male
- Female
- Hemic and lymphatic
- Immune system
- Digestive system
- Respiratory tract
- Male
- Female
- Hemic and lymphatic
- Proteases
- PPI modulators
References: we are preparing a list of scientific research reports with L575-0187 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)