L575-0245 Screening compound: N-{2-[cyclohexyl(methyl)amino]ethyl}-4-[1-methyl-3-(pyrrolidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-4-oxobutanamide

L575-0245 Screening compound: N-{2-[cyclohexyl(methyl)amino]ethyl}-4-[1-methyl-3-(pyrrolidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-4-oxobutanamide
L575-0245 Screening compound: N-{2-[cyclohexyl(methyl)amino]ethyl}-4-[1-methyl-3-(pyrrolidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-4-oxobutanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L575-0245
N-{2-[cyclohexyl(methyl)amino]ethyl}-4-[1-methyl-3-(pyrrolidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-4-oxobutanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L575-0245

Molecular Formula

C25H40N6O3 (C25 H40 N6 O3)

Compound Name

N-{2-[cyclohexyl(methyl)amino]ethyl}-4-[1-methyl-3-(pyrrolidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-4-oxobutanamide

IUPAC name

N-{2-[cyclohexyl(methyl)amino]ethyl}-4-[1-methyl-3-(pyrrolidine-1-carbonyl)-1H4H5H6H7H-pyrazolo[43-c]pyridin-5-yl]-4-oxobutanamide

SMILES

CN(CCNC(CCC(N(CC1)Cc2c1n(C)nc2C(N1CCCC1)=O)=O)=O)C1CCCCC1

InChI

InChI=1S/C25H40N6O3/c1-28(19-8-4-3-5-9-19)17-13-26-22(32)10-11-23(33)31-16-12-21-20(18-31)24(27-29(21)2)25(34)30-14-6-7-15-30/h19H,3-18H2,1-2H3,(H,26,32)

InChI Key

KDNGQOLBKVDRCA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27463503

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.63

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.137

Distribution Coefficient, logD

-1.516

Water Solubility, LogSw

-0.75

Polar Surface Area

75.404

Acid Dissociation Constant (pKa)

13.73

Base Dissociation Constant (pKb)

9.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

76.00

L575-0245 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

GPCR Targeted Library (31838 compounds)

Hsp90-Targeted Library (11355 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Targets:
  • Proteases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L575-0245 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L575-0245?
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What is the minimum amount of L575-0245 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L575-0245
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L575-0245
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L575-0245 available by request