L575-0347 Screening compound: 1-{[1,4'-bipiperidin]-1'-yl}-4-[1-methyl-3-(piperidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]butane-1,4-dione

L575-0347 Screening compound: 1-{[1,4'-bipiperidin]-1'-yl}-4-[1-methyl-3-(piperidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]butane-1,4-dione
L575-0347 Screening compound: 1-{[1,4'-bipiperidin]-1'-yl}-4-[1-methyl-3-(piperidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]butane-1,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound L575-0347
1-{[1,4'-bipiperidin]-1'-yl}-4-[1-methyl-3-(piperidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]butane-1,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L575-0347

Molecular Formula

C27H42N6O3 (C27 H42 N6 O3)

Compound Name

1-{[1,4'-bipiperidin]-1'-yl}-4-[1-methyl-3-(piperidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]butane-1,4-dione

IUPAC name

1-{[14'-bipiperidin]-1'-yl}-4-[1-methyl-3-(piperidine-1-carbonyl)-1H4H5H6H7H-pyrazolo[43-c]pyridin-5-yl]butane-14-dione

SMILES

Cn1nc(C(N2CCCCC2)=O)c(C2)c1CCN2C(CCC(N(CC1)CCC1N1CCCCC1)=O)=O

InChI

InChI=1S/C27H42N6O3/c1-29-23-12-19-33(20-22(23)26(28-29)27(36)32-15-6-3-7-16-32)25(35)9-8-24(34)31-17-10-21(11-18-31)30-13-4-2-5-14-30/h21H,2-20H2,1H3

InChI Key

DSDDLAQABXFFFY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27463532

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.67

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.604

Distribution Coefficient, logD

-2.952

Water Solubility, LogSw

-0.40

Polar Surface Area

67.173

Acid Dissociation Constant (pKa)

22.09

Base Dissociation Constant (pKb)

10.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

77.80

L575-0347 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L575-0347 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L575-0347?
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What is the minimum amount of L575-0347 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L575-0347
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L575-0347
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L575-0347 available by request