L575-0368 Screening compound: 4-[1-methyl-3-(piperidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-4-oxo-N-(4-phenylbutan-2-yl)butanamide

L575-0368 Screening compound: 4-[1-methyl-3-(piperidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-4-oxo-N-(4-phenylbutan-2-yl)butanamide
L575-0368 Screening compound: 4-[1-methyl-3-(piperidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-4-oxo-N-(4-phenylbutan-2-yl)butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L575-0368
4-[1-methyl-3-(piperidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-4-oxo-N-(4-phenylbutan-2-yl)butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L575-0368

Molecular Formula

C27H37N5O3 (C27 H37 N5 O3)

Compound Name

4-[1-methyl-3-(piperidine-1-carbonyl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-4-oxo-N-(4-phenylbutan-2-yl)butanamide

IUPAC name

4-[1-methyl-3-(piperidine-1-carbonyl)-1H4H5H6H7H-pyrazolo[43-c]pyridin-5-yl]-4-oxo-N-(4-phenylbutan-2-yl)butanamide

SMILES

CC(CCc1ccccc1)NC(CCC(N(CC1)Cc2c1n(C)nc2C(N1CCCCC1)=O)=O)=O

InChI

InChI=1S/C27H37N5O3/c1-20(11-12-21-9-5-3-6-10-21)28-24(33)13-14-25(34)32-18-15-23-22(19-32)26(29-30(23)2)27(35)31-16-7-4-8-17-31/h3,5-6,9-10,20H,4,7-8,11-19H2,1-2H3,(H,28,33)/t20-/m0/s1

InChI Key

HJEGTZRDWIIOQJ-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD27463537

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.62

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.737

Distribution Coefficient, logD

1.737

Water Solubility, LogSw

-2.21

Polar Surface Area

71.600

Acid Dissociation Constant (pKa)

14.89

Base Dissociation Constant (pKb)

3.55

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

55.60

L575-0368 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L575-0368 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L575-0368?
Check Price and Availability of L575-0368, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L575-0368 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L575-0368
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L575-0368
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L575-0368 available by request